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Hebei Sankai Chemical Technology Co., Ltd
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Methylprednisolone aceponate

Methylprednisolone aceponate CAS NO.86401-95-8

  • FOB Price: USD: 50.00-100.00 /Kilogram Get Latest Price
  • Min.Order: 1 Kilogram
  • Payment Terms: T/T,MoneyGram,Other
  • Available Specifications:

    一(1-100)Kilogram一(100-1000)Kilogram

  • Product Details

Keywords

  • Methylprednisolone aceponate
  • Methylprednisoloni aceponas [Latin]
  • Advantan

Quick Details

  • ProName: Methylprednisolone aceponate
  • CasNo: 86401-95-8
  • Molecular Formula: C27H36O7
  • Appearance: White powder
  • Application: Ribociclib succinate (LEE011 succinate...
  • DeliveryTime: 3-7days
  • PackAge: fiber can
  • Port: Tianjin Xingang/Qingdao Port
  • ProductionCapacity: 100 Metric Ton/Month
  • Purity: 98%
  • Storage: Seal and store in a cool and dry place
  • Transportation: By sea/air/land
  • LimitNum: 1 Kilogram

Superiority

1. Product advantages
High purity, all above 98.5%, no impurities after dissolution
We will test each batch to ensure quality
OEM and private brand services designed for free
Various cap colors available
We can also provide MT1 peptide powder
2. Factory advantages
Professional research team
More than 5 doctors in high-tech R&D laboratories
More than 1000 m2 of factory production line to ensure stable supply
More than 1200 factories to manufacture products and control quality
3. Service advantages
24-hour online service
Track package information and update it for customers
Professional sales team
Accept small order service
Redelivery service if detained by customs

Details

Product Introduction:

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Methylprednisolone acetate (ZK 91588) is a glucocorticoid and anti-inflammatory drug with weak systemic effects. Acetylprednisolone is a selective glucocorticoid receptor ligand. Acetylmethylprednisolone can be used for research on eczema and other inflammatory skin diseases [1] [2] [3].
Related categories
Research Fields>>Inflammation/Immunology
Signal Pathways>>G Protein Coupled Receptors/G Proteins>>Glucocorticoid Receptors
In vitro studies on the inhibition of collagenase promoter activity by methylprednisolone acetate (in Hela cells), IL-12p40 secretion induced by lipopolysaccharide (in human PBMC cells), and interferon induced by plant agglutinin- γ Secretion (in human PBMC company), integrated circuit 50 is 9.3, 16.8, and 15.2 nM, respectively [3]. Methylprednisolone acetate activated the millimeter TV promoter and Tate activity, which were 21.8 and 20.5 nM at week 50, respectively [3]
In vivo study of methylprednisolone acetate (topical application, 50 μ, The Ivan blue edema model caused by croton oil has anti-inflammatory effects, with an international 50 of 0.0015% and low systemic side effects [1]. Methylprednisolone acetate (0.0001% -0.1% local application) inhibits edema formation in irritating contact dermatitis in mice and rats, with a 50th edition of 0.002% [3]. Animal model: Stimulating contact dermatitis in mice and rats [3] Dose: 0.0001% -0.1% Administration: Local application, 10 µ L in mice and 20 µ L in rats. Result: Significant inhibition of ear canal inflammation.

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