Hebei Sankai Chemical Technology Co., Ltd

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Hebei Sankai Chemical Technology Co., Ltd
Country:  China (Mainland)
Business Type:  Trading Company
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Mr.shao
Tel: +86 15932099601
Mr.Dylan
Tel: +8619565625236
Ms.Cassie
Tel: +86 15803298103
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URL:  http://86-sk.com
City:  邢台
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(S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline CAS:118864-75-8

(S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline CAS:118864-75-8 CAS NO.118864-75-8

  • FOB Price: USD: 20.00-50.00 /Kilogram Get Latest Price
  • Min.Order: 1 Kilogram
  • Payment Terms: T/T,MoneyGram,Other
  • Available Specifications:

    1(1-10)Kilogram1(10-100)Kilogram1(100-1000)Kilogram

  • Product Details

Keywords

  • S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline
  • Isoquinoline, 1,2,3,4-tetrahydro-1-phenyl-, (1S)-
  • Solifenacin Related Compound 11

Quick Details

  • ProName: (S)-1-Phenyl-1,2,3,4-tetrahydroisoquin...
  • CasNo: 118864-75-8
  • Molecular Formula: C15H15N
  • Appearance: white powder
  • Application: scientific research
  • DeliveryTime: 3-7Days
  • PackAge: Bag/bucket
  • Port: Tianjin New Harbour/qingdao port
  • ProductionCapacity: 10000 Metric Ton/Year
  • Purity: 99%
  • Storage: under inert gas (nitrogen or Argon) at...
  • Transportation: by air or by sea
  • LimitNum: 1 Kilogram

Superiority

1. Product advantages

♦ High purity, all above 98.5%, no impurities after dissolution

♦ We will test each batch to ensure quality

♦ OEM and private brand services designed for free

♦ Various cap colors available

♦ We can also provide MT1 peptide powder

2. Factory advantages

♦ Professional research team

♦ More than 5 doctors in high-tech R&D laboratories

♦ More than 1000 m2 of factory production line to ensure stable supply

♦ More than 1200 factories to manufacture products and control quality

3. Service advantages

♦ 24-hour online service

♦ Track package information and update it for customers

♦ Professional sales team

♦ Accept small order service

♦ Redelivery service if detained by customs

Details

(S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline is white to off-white powder.

Density 1.1± 0.1g /cm3

Boiling point 338.4±11.0 °C at 760 mmHg

Melting point 80-82ºC

Molecular formula C15H15N

Molecular weight 209.286

Flash point 166.9±14.7 °C

Accurate mass 209.120453

PSA 12.03000

LogP is 2.70

Appearance properties white solid

Vapor pressure 0.0±0.7 mmHg at 25°C

Refractive index 1.589

Application:

(S) -1-phenyl-1,2,3, 4-tetrahydroisoquinoline can be used to prepare sofinaxine. SolifenacinSuccinate, CAS No. 242478-38-2, chemical name 1-azazobicyclic [2.2.2] octane-8-group -(1S) -1-phenyl-3, 4-dihydro-1h-isoquinoline-2-formate succinate, It is a selective muscarinic M3 receptor antagonist developed by Astellas in Japan. It was first marketed in Netherlands, Germany, UK and Denmark in 2004, and in China in 2009. So far, it has been marketed in more than 50 countries and regions around the world. It has become an important drug for the treatment of overactive bladder (OAB) in Europe, the United States and Japan, and has been recommended by several authorities and guidelines. Its preparation is as follows: (S) -1-phenyl-1,2,3, 4-tetrahydroisoquinoline (I) was synthesized by reaction condensation with triphosgene under the condition of organic base (weak base). (S) -1-phenyl-3, 4-dihydro-1h-isoquinoline-2-formyl chloride (II) was obtained. Compound II was heated directly under the catalysis of organic base by one-pot method without separation. It was condensed with (R) -3-quininocyclol to obtain Solinaxine (III), which was then salted with succinic acid to produce Solinaxine (IV) succinate.

Package:

Delivery:

Our company has long-term cooperation with many world-famous logistics companies to ensure transportation efficiency and cargo safety. 

FAQ:

1. How do you control the quality   
Our factory is equipped with professional technicians to control quality, out inspectors take sample for testing every 2 hours to ensure the quality of our production. We also accept BV, SGS or any other Third-party inspection.   

2.  How long is lead time  
We deliver goods within 3 days for small order, 7-10 days for bulk order.   

3.  Can I get some samples 
 Yes, we can supply free sample, but the shipping cost be paid by our customers. 

4.  How long is lead time

We deliver goods within 3 days for small order, 7-10 days for bulk order.

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