Hebei Sankai Chemical Technology Co., Ltd

New raw materials, fertilizer,food, feed additives, cosmetics, dyes and industrial chemicals
Assessed Supplier
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th
year
Hebei Sankai Chemical Technology Co., Ltd
Country:  China (Mainland)
Business Type:  Trading Company
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Supplier
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Mr.shao
Tel: +86 15932099601
Mr.Dylan
Tel: +8619565625236
Ms.Cassie
Tel: +86 15803298103
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URL:  http://86-sk.com
City:  邢台
Street:  hebei
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Cimetropium bromide

Cimetropium bromide CAS NO.51598-60-8

  • FOB Price: USD: 50.00-100.00 /Kilogram Get Latest Price
  • Min.Order: 1 Kilogram
  • Payment Terms: T/T,MoneyGram,Other
  • Available Specifications:

    一(1-100)Kilogram一(100-1000)Kilogram

  • Product Details

Keywords

  • Cimetropium bromide
  • Cimetropiumbromid
  • N-Cyclopropvlmethylscopolamine bromide

Quick Details

  • ProName: Cimetropium bromide
  • CasNo: 51598-60-8
  • Molecular Formula: C21H28BrNO4
  • Appearance: White powder
  • Application: Ribociclib succinate (LEE011 succinate...
  • DeliveryTime: 3-7days
  • PackAge: fiber can
  • Port: Tianjin Xingang/Qingdao Port
  • ProductionCapacity: 100 Metric Ton/Month
  • Purity: 98%
  • Storage: Seal and store in a cool and dry place
  • Transportation: By sea/air/land
  • LimitNum: 1 Kilogram

Superiority

1. Product advantages
High purity, all above 98.5%, no impurities after dissolution
We will test each batch to ensure quality
OEM and private brand services designed for free
Various cap colors available
We can also provide MT1 peptide powder
2. Factory advantages
Professional research team
More than 5 doctors in high-tech R&D laboratories
More than 1000 m2 of factory production line to ensure stable supply
More than 1200 factories to manufacture products and control quality
3. Service advantages
24-hour online service
Track package information and update it for customers
Professional sales team
Accept small order service
Redelivery service if detained by customs

Details

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Product Introduction:
Cimetropium Bromide is a muscarinic receptor antagonist used for long-term treatment of irritable bowel syndrome.
Related categories
Signal Pathways>>G Protein Coupled Receptors/G Proteins>>By mAChR
Signal Pathways>>Neural Signal Pathways>>mAChR
Research Fields>>Inflammation/Immunology
Research Fields>>Neurological Diseases
Target point
MAChR 
In vitro study of Cimetropium Bromide as a competitive antagonist against muscarine mediated contraction in two species of isolated colon preparations, with affinity values (pA2) between 7.41 and 7.82 . Cimetropium has effective anti muscarinic effects and can inhibit the contraction of longitudinal muscle preparations. In the perfusion experiment of pre loaded choline labeled formulations, cilphthalocyanine reduced the release of labeled ACh induced by electric field stimulation under self inhibitory conditions of muscarinic acid .
In vivo research shows that Cimetropium is an effective inhibitor of colon motility caused by both exogenous and endogenous stimuli when administered intravenously to conscious dogs with colon Third fistula. Cimetropium Bromide (10-100 μ G/kg) counteracts the colonic motility response of neostigmine administration, with an ID50 of 27.9 μ G/kg; The rigidity and stage components of the contraction response are affected. Within a considerable dose range (3-100 μ In g/kg, this drug can inhibit motor activity caused by intracavitary dilation .

 

Hebei Sankai Chemical Technology Co., Ltd. is a new chemical enterprise integrating the research, manufacturing and supply of chemicals. Located in the beautiful "cattle city" Xingtai, Hebei Sankai Chemical Technology Co., Ltd. is mainly engaged in the research of chemical fertilizer. At the same time, we have made great breakthroughs in food, feed additives, cosmetics, dyes and industrial chemicals. Our company spirit of "integrity management, quality control, customer first" belief, at home and abroad enjoy high reputation.

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