1. Product advantages
High purity, all above 98.5%, no impurities after dissolution
We will test each batch to ensure quality
OEM and private brand services designed for free
Various cap colors available
We can also provide MT1 peptide powder
2. Factory advantages
Professional research team
More than 5 doctors in high-tech R&D laboratories
More than 1000 m2 of factory production line to ensure stable supply
More than 1200 factories to manufacture products and control quality
3. Service advantages
24-hour online service
Track package information and update it for customers
Professional sales team
Accept small order service
Redelivery service if detained by customs

Produc tIntroduction:

Boiling point bp0.1 120°

Density 0.924± 0.06g /cm3(Predicted)

Solubility Chloroform (Slightly), Methanol (Slightly)

Acidity coefficient (pKa)7.33±0.10(Predicted)

CAS DataBase 78613-35-1(CAS DataBase Reference)

Amorolfine is a derivative of phenpromorpholine, developed by Roche and marketed in 1991 under the trade name Leceryl, which mainly inhibits the synthesis of ergosterol, one of the membrane components of fungal cell membranes. Unlike some azole drugs and bicycin B, it does not affect the phagocytosis activity of human neutrophils, but increases its adhesion ability. Increased intercellular lethality was observed when neutrophils were co-cultured with amolprofen.

The target enzymes of amerolofen action are △14 reductase and △8→△7 isomerase in the sterol synthesis pathway, which hinder the synthesis of ergosterol, while squalene, ignosterol, ergosta-8,14,24(28)-trien-3β accumulate in the membrane, resulting in changes in the content of sterols in the membrane. The changes of membrane permeability caused by the introduction of Chemicalbook affect the metabolic process of fungi. At the same time, amolprofen also caused abnormal chitin deposition, which led to fungal growth disorder. It also inhibited the activities of NADH oxidase and succinate cytochrome C reductase. In vitro studies have shown that it can significantly reduce the adhesion of Candida albicans to human tissue cells as well as azole derivatives.

New broad-spectrum antifungal agent. It is the first product in morpholine biology. Acting by inhibiting a particular stage of the ergosterol biosynthesis pathway, the Chemicalbook penetrates and diffuses towards the nail, thereby producing long-lasting antifungal effects. Not only can the skin fungal infection be successfully eradicated, but also the onychomycosis infection (tinea onychomycosis). For skin fungus, yeast and mold caused by tinea

The mechanism of action of topical antifungal agents is different from other existing antifungal agents. It inhibits two enzymes in ergosterol biosynthesis, reductase and isomerase. In vitro, it has very high Chemicalbook antifungal activity, and in vivo activity is better than naftifen, clotrimazole, oxicconazole and ketoconazole. The cure rate of various fungal skin diseases is more than 85%, and it has special effect on tinea onychomycosis

Hebei Sankai Chemical Technology Co., Ltd. is a new chemical enterprise integrating the research, manufacturing and supply of chemicals. Located in the beautiful "cattle city" Xingtai, Hebei Sankai Chemical Technology Co., Ltd. is mainly engaged in the research of chemical fertilizer. At the same time, we have made great breakthroughs in food, feed additives, cosmetics, dyes and industrial chemicals. Our company spirit of "integrity management, quality control, customer first" belief, at home and abroad enjoy high reputation.