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China (Mainland)
QUININE SULFATE CAS804-63-7 CAS NO.804-63-7
- FOB Price: USD: 289.00-499.00 /Kilogram Get Latest Price
- Min.Order: 1 Kilogram
- Payment Terms: T/T,Other
- Available Specifications:
一(1-10)Kilogram一(11-100)Kilogram一(101-1000)Kilogram
- Product Details
Keywords
- QUININE SULFATE
- quinine hydrogen sulphate
- Chemcial
Quick Details
- ProName: QUININE SULFATE CAS804-63-7
- CasNo: 804-63-7
- Molecular Formula: C20H26N2O6S
- Appearance: White powder
- Application: Quinoquine sulfate (2:1) (quilaquine) ...
- DeliveryTime: 3-7days
- PackAge: fiber can
- Port: Tianjin Xingang/Qingdao Port
- ProductionCapacity: 100 Metric Ton/Month
- Purity: 98%
- Storage: Seal and store in a cool and dry place
- Transportation: By sea/air/land
- LimitNum: 1 Kilogram
Superiority
1. Product advantages
♦ High purity, all above 98.5%, no impurities after dissolution
♦ We will test each batch to ensure quality
♦ OEM and private brand services designed for free
♦ Various cap colors available
♦ We can also provide MT1 peptide powder
2. Factory advantages
♦ Professional research team
♦ More than 5 doctors in high-tech R&D laboratories
♦ More than 1000 m2 of factory production line to ensure stable supply
♦ More than 1200 factories to manufacture products and control quality
3. Service advantages
♦ 24-hour online service
♦ Track package information and update it for customers
♦ Professional sales team
♦ Accept small order service
♦ Redelivery service if detained by customs
Details
Biological Activity
| description | Quinoquine sulfate (2:1) (quilaquine) is an orally active alkaloid extracted from the bark of the cinchona tree that can be used in antimalarial research. Qunine sulfate (2:1) is a potassium channel inhibitor that inhibits the WT mouse Slo3 (KCa5.1) channel current, which is caused by a voltage pulse of +100 mV with an IC50 of 169 μM[1][2]. |
|---|---|
| Related categories |
Signaling pathway >> transmembrane transport >> potassium channels |
| In vitro studies | Qunine sulfate (150 μM, 30 min) inhibits dengue virus proliferation and cytostatic effects in human liver cancer HepG2 cell lines[1]. Quinine sulfate (37.5-150 μM, 24 h) significantly reduces viral DENV RNA and protein levels in human hepatic carcinoma HepG2 cell lines in a dose-dependent manner[1]. Cell proliferation assay[1] Cell line: Human hepatoma cell line (HepG2) Concentration: 150 μM Incubation Time: 30 min Result: Inhibition of DENV virus replication compared to untreated with a yield of 19%. DENV-positive cells were reduced from 23.28% to 12.05% in a dose-dependent manner. |
| In vivo research | Quinine sulfate (oral gavage, 12 or 15 mg/kg weekly, 16 weeks) has some inhibitory effect on skin cancer in Swiss albino mice[2]. Qunine sulfate (oral, 10 mg/kg daily, for 8 weeks) results in decreased antioxidant defense systems (e.g., SOD, CAT, and GSH enzyme activity) in testis tissues of male adult albino rats[3]. Animal model: 7-8 weeks (body weight 24 g) of Swiss albino mice[2] Dose: 12 mg/kg, 15 mg/kg administration: oral gavage; Weekly; 16 weeks Result: Tumor size and weight were significantly reduced at a dose of 12 mg/kg, while at a higher dose of 15 mg/kg, the effect was minimal. |
| References |
Package
Delivery
Our company has long-term cooperation with many world-famous logistics companies to ensure transportation efficiency and cargo safety.
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By Express |
By air |
By Sea |
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Suitable for under 50kg |
Suitable for more than 50kg |
Suitable for more than 500kg |
FAQ
1. Are you a trade company or factory
We are a factory with our own trading company.
2. How long is lead time
We deliver goods within 3 days for small order, 7-10 days for bulk order.
3. Where is your factory located How can I visit the factory
Our factory located in WEIFANG, China. It is only two hours from QINGDAO.
4. Can i get some samples
Yes, we can supply free sample, but the shipping cost be paid by our customers.
5. How to start orders or make payments
Proforma invoice will be sent first after confirmation of order, enclosed our bank information.Payment by T/T,
6. How to confirm the Product Quality before placing orders
You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples.
You can send us your product specifications and requests,we will manufacture the products according to your requests.